STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BD01_0218Putative transcriptional regulators; COG1378. (264 aa)    
Predicted Functional Partners:
rgy
Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
     
 0.607
BD01_0024
Phosphomannomutase; COG1109.
 
     0.499
BD01_0826
Hypothetical protein.
  
     0.498
BD01_0216
Hypothetical protein.
       0.467
BD01_0621
Putative solute binding protein; COG3889.
  
     0.461
BD01_1417
Putative solute binding protein; COG3889.
  
     0.460
BD01_0205
Hypothetical protein.
  
     0.452
BD01_0184
Putative transcriptional regulators; COG1777.
  
   
 0.441
rpl35ae
Ribosomal protein L35AE; Belongs to the eukaryotic ribosomal protein eL33 family.
  
     0.440
BD01_1801
Putative transcriptional regulators; COG0640.
  
   
 0.433
Your Current Organism:
Thermococcus nautili
NCBI taxonomy Id: 195522
Other names: CNCM 4275, JCM 19601, T. nautili, Thermococcus nautili Gorlas et al. 2014, Thermococcus nautilus, Thermococcus sp. 30-1, strain 30-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.