STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BD01_0407Uncharacterized protein conserved in archaea; COG1817. (366 aa)    
Predicted Functional Partners:
BD01_0406
UDP-N-acetyl-D-mannosaminuronate dehydrogenase; COG0677; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
 
   
 0.699
BD01_0405
UDP-N-acetylglucosamine 2-epimerase; COG0381.
 
    0.685
BD01_1875
Putative RNA-binding protein, contains THUMP domain; COG1818.
  
     0.662
BD01_1912
Putative Ser/Thr protein kinase; COG2112.
  
     0.572
priS
Eukaryotic-type DNA primase, catalytic (small) subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer exten [...]
  
     0.515
BD01_1705
Putative cell wall-binding domain; COG2247.
  
    0.493
BD01_0233
Transcription elongation factor; COG0195.
  
     0.469
BD01_0247
Probable Brix domain-containing ribosomal biogenesis protein; Probably involved in the biogenesis of the ribosome.
  
     0.468
BD01_0815
Asparagine synthase (glutamine-hydrolyzing); COG0367.
 
   
 0.461
BD01_1281
UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; COG0472.
 
     0.432
Your Current Organism:
Thermococcus nautili
NCBI taxonomy Id: 195522
Other names: CNCM 4275, JCM 19601, T. nautili, Thermococcus nautili Gorlas et al. 2014, Thermococcus nautilus, Thermococcus sp. 30-1, strain 30-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.