STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BD01_0905Zn-dependent hydrolase, including glyoxylase; COG0491. (236 aa)    
Predicted Functional Partners:
BD01_0906
Uncharacterized protein conserved in archaea; COG1531; Belongs to the UPF0248 family.
       0.819
BD01_0909
SAM-dependent methyltransferase; COG0500.
  
 
 0.734
BD01_0904
Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase-related deacylase; COG0624.
  
  
 0.707
truA
Pseudouridylate synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family.
   
 
 0.575
rps17
Ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
  
   0.478
BD01_0898
Alcohol dehydrogenase, class IV; COG1454.
 
 
 0.437
BD01_1053
Ribosomal protein L9.
 
  
 0.416
rpl37e
Ribosomal protein L37E (rpl37E); Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family.
  
   0.415
BD01_2183
16S RNA G1207 methylase RsmC; COG2813.
   
   0.410
nth
Putative EndoIII-related endonuclease; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
   
 0.407
Your Current Organism:
Thermococcus nautili
NCBI taxonomy Id: 195522
Other names: CNCM 4275, JCM 19601, T. nautili, Thermococcus nautili Gorlas et al. 2014, Thermococcus nautilus, Thermococcus sp. 30-1, strain 30-1
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