STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mptEPutative Rossmann fold enzyme; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP). (256 aa)    
Predicted Functional Partners:
BD01_0325
Dihydropteroate synthase-related enzyme; COG0294.
 
  
 0.941
BD01_0354
Metal-dependent hydrolases of the beta-lactamase superfamily II; COG1237.
    
  0.901
BD01_0558
Metal-dependent hydrolases of the beta-lactamase superfamily II; COG1237.
    
  0.901
BD01_0910
Dihydropteroate synthase-related enzyme; COG0294.
 
   
 0.597
BD01_0945
Hypothetical protein; COG1469.
 
   
 0.593
BD01_1091
ABC-type dipeptide transport system, periplasmic component; COG0747.
       0.550
BD01_1507
Ribosomal protein S24E; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
  
     0.517
BD01_2136
Putative membrane protein; COG2237.
 
     0.513
BD01_0582
GTP:adenosylcobinamide-phosphate guanylyltransferase; COG2266.
 
     0.512
tiaS
Putative DNA-binding protein containing a Zn-ribbon domain; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
  
     0.479
Your Current Organism:
Thermococcus nautili
NCBI taxonomy Id: 195522
Other names: CNCM 4275, JCM 19601, T. nautili, Thermococcus nautili Gorlas et al. 2014, Thermococcus nautilus, Thermococcus sp. 30-1, strain 30-1
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