STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BD01_1675Dephospho-CoA kinase; COG0237; Belongs to the UPF0200 family. (190 aa)    
Predicted Functional Partners:
BD01_1673
Uncharacterized protein conserved in archaea; COG1931; Belongs to the UPF0201 family.
    0.854
hel308
Superfamily II helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
     
 0.743
BD01_1507
Ribosomal protein S24E; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
  
   
 0.530
BD01_1288
Putative Zn-ribbon RNA-binding protein with a function in translation; COG2888.
  
     0.519
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
    0.512
BD01_1677
Putative transcription regulator.
       0.485
BD01_1978
Uncharacterized protein conserved in archaea; COG1701.
 
     0.476
gap
Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; COG0057.
 
   
 0.455
dnaG
DNA primase (bacterial type); RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
 
  
 0.434
BD01_1813
Archaeal enzymes of ATP-grasp superfamily; COG1938.
 
     0.428
Your Current Organism:
Thermococcus nautili
NCBI taxonomy Id: 195522
Other names: CNCM 4275, JCM 19601, T. nautili, Thermococcus nautili Gorlas et al. 2014, Thermococcus nautilus, Thermococcus sp. 30-1, strain 30-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.