STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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nadKPutative sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (278 aa)    
Predicted Functional Partners:
nadE
NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
    
 0.967
cobB
NAD-dependent protein deacetylase, SIR2 family; COG0846; Belongs to the sirtuin family. Class III subfamily.
  
 
 0.938
BD01_1032
Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family; COG0483.
 
  
 0.931
BD01_1844
tRNA and rRNA cytosine-C5-methylase; COG0144; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
    0.929
BD01_1125
Ribosomal protein S27E.
    
 0.927
BD01_1843
Putative integral membrane protein; COG0392.
       0.812
BD01_1845
Hypothetical protein.
       0.812
BD01_1987
Nicotinic acid phosphoribosyltransferase; COG1488.
 
   
 0.734
BD01_1846
Conserved secreted protein; COG5608.
       0.731
uppS
Undecaprenyl pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
 
   
 0.642
Your Current Organism:
Thermococcus nautili
NCBI taxonomy Id: 195522
Other names: CNCM 4275, JCM 19601, T. nautili, Thermococcus nautili Gorlas et al. 2014, Thermococcus nautilus, Thermococcus sp. 30-1, strain 30-1
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