STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BD01_1902Coenzyme F420-reducing hydrogenase, alpha subunit; COG3259. (390 aa)    
Predicted Functional Partners:
BD01_1901
Coenzyme F420-reducing hydrogenase, gamma subunit; COG1941.
 
 0.999
BD01_1900
Coenzyme F420-reducing hydrogenase, beta subunit; COG1035.
 
 0.998
BD01_2062
NADPH-dependent glutamate synthase beta chain-related oxidoreductase; COG0493.
  
 
 0.917
BD01_0438
Coenzyme F420-reducing hydrogenase, gamma subunit; COG1941.
 
 
 0.880
BD01_2067
Coenzyme F420-reducing hydrogenase, gamma subunit; COG1941.
 
 
 0.878
hypA
Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.845
BD01_0114
Hydrogenase maturation factor; COG0068.
 
 
 
 0.829
BD01_0115
Hydrogenase maturation factor; COG0409.
 
 
 0.822
BD01_0111
Hydrogenase maturation factor; COG0309.
 
   
 0.730
BD01_1899
Anaerobic dehydrogenase, typically selenocysteine-containing; COG0243.
  
 
 0.611
Your Current Organism:
Thermococcus nautili
NCBI taxonomy Id: 195522
Other names: CNCM 4275, JCM 19601, T. nautili, Thermococcus nautili Gorlas et al. 2014, Thermococcus nautilus, Thermococcus sp. 30-1, strain 30-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.