STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BD01_2032Putative proteins of PilT N-term/Vapc superfamily; COG1412. (138 aa)    
Predicted Functional Partners:
BD01_0950
Putative RNA-binding protein (contains KH domains); COG1094.
  
 0.989
eif2g
Translation initiation factor 2, gamma subunit (eIF-2gamma, GTPase); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
 
    0.816
rps6e
Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
   
 0.775
rpoL
DNA-directed RNA polymerase, subunit L; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
  
    0.737
nep1
Hypothetical protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.
   
 0.736
BD01_1387
Protein involved in ribosomal biogenesis, contains PUA domain; COG1374.
   
    0.706
BD01_1732
Protein implicated in ribosomal biogenesis, Nop56p-like protein; COG1498.
   
 
 0.691
BD01_0247
Probable Brix domain-containing ribosomal biogenesis protein; Probably involved in the biogenesis of the ribosome.
  
    0.673
BD01_0097
NMD protein affecting ribosome stability and mRNA decay; COG1499.
 
    0.649
rnp2
RNase P/RNase MRP subunit POP5; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
  
    0.640
Your Current Organism:
Thermococcus nautili
NCBI taxonomy Id: 195522
Other names: CNCM 4275, JCM 19601, T. nautili, Thermococcus nautili Gorlas et al. 2014, Thermococcus nautilus, Thermococcus sp. 30-1, strain 30-1
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.