STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BD01_2144Mn-dependent transcriptional regulator; COG1321. (140 aa)    
Predicted Functional Partners:
BD01_0954
ABC-type Mn2+/Zn2+ transport systems, permease components; COG1108.
  
  
 0.772
BD01_0775
ABC-type metal ion transport system, periplasmic component/surface adhesin; COG0803.
  
  
 0.763
BD01_0953
Ribosomal protein L34.
  
  
 0.753
BD01_1674
Putative divalent heavy-metal cations transporter; COG0428.
  
  
 0.630
dphB
Diphthamide biosynthesis methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.
       0.598
BD01_0765
Fe2+ transport system protein B; COG0370.
 
  
 0.529
BD01_0127
Ni,Fe-hydrogenase III small subunit; COG3260.
    
   0.512
BD01_1884
NADH dehydrogenase subunit B.
    
   0.512
BD01_0764
Fe2+ transport system protein A; COG1918.
  
  
 0.511
BD01_0187
DNA-directed RNA polymerase, beta subunit/140 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.431
Your Current Organism:
Thermococcus nautili
NCBI taxonomy Id: 195522
Other names: CNCM 4275, JCM 19601, T. nautili, Thermococcus nautili Gorlas et al. 2014, Thermococcus nautilus, Thermococcus sp. 30-1, strain 30-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.