STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BD01_2174Putative membrane protein; COG1422. (174 aa)    
Predicted Functional Partners:
adkA
Archaeal adenylate kinase; COG2019; Belongs to the archaeal adenylate kinase family.
 
    0.924
cmk
Cytidylate kinase; COG1102.
 
     0.781
secY
Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
 
    0.778
rps5
Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.
 
    0.762
rpl15
Ribosomal protein L15P (rpl15P); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
  
    0.735
rpl30
Ribosomal protein L30P (rpl30P).
 
    0.734
rpl34e
Ribosomal protein L34E (rpl34E); Belongs to the eukaryotic ribosomal protein eL34 family.
       0.734
rpl14e
Ribosomal protein L14E (rpl14E); Belongs to the eukaryotic ribosomal protein eL14 family.
       0.729
rpl32e
Ribosomal protein L32; Belongs to the eukaryotic ribosomal protein eL32 family.
 
    0.716
rpl3
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
 
    0.669
Your Current Organism:
Thermococcus nautili
NCBI taxonomy Id: 195522
Other names: CNCM 4275, JCM 19601, T. nautili, Thermococcus nautili Gorlas et al. 2014, Thermococcus nautilus, Thermococcus sp. 30-1, strain 30-1
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