STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ileSisoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (921 aa)    
Predicted Functional Partners:
argS
arginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.968
glnS
glutamine--tRNA ligase; Catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.952
leuS
leucine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
0.951
lspA
Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
  
  
 0.882
lysS
lysine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 0.870
OPX32533.1
valine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
0.841
asnS
asparagine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.810
OPX32453.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.786
OPX32456.1
Carbamate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbamate kinase family.
       0.780
OPX32451.1
YggU family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0235 family.
       0.755
Your Current Organism:
Gemmatimonadaceae bacterium 4484173
NCBI taxonomy Id: 1956166
Other names: G. bacterium 4484_173, Gemmatimonadaceae bacterium 4484_173
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.