STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
guaB1Putative oxidoreductase. (480 aa)    
Predicted Functional Partners:
guaA
GMP synthase [glutamine-hydrolyzing].
 
 0.998
purA
Adenylosuccinate synthetase.
 
 
 0.980
purH
Bifunctional purine biosynthesis protein PurH.
 
 
 0.955
guaB_1
Inosine-5'-monophosphate dehydrogenase.
 
  
0.947
gltB
Glutamate synthase [NADPH] large chain.
  
 
 0.941
GCA_000715605_03771
Non-canonical purine NTP pyrophosphatase.
 
 0.938
hpt
Hypoxanthine-guanine phosphoribosyltransferase.
    
 0.903
yhcR
Endonuclease YhcR.
    
 0.895
GCA_000715605_03536
Putative oxidoreductase/MSMEI_1564.
    
 0.887
mazG
Nucleoside triphosphate pyrophosphohydrolase.
    
  0.886
Your Current Organism:
Streptomyces speibonae
NCBI taxonomy Id: 195801
Other names: ATCC BAA-411, CIP 108060, DSM 41797, JCM 12682, KCTC 9973, NBRC 101001, NRRL B-24240, S. speibonae, Streptomyces speibonae Meyers et al. 2003, strain PK-Blue
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