ABCF2 protein (Laodelphax striatellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Cooccurrence

Coexpression

Experiments

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[Homology]

Score

ABCF2

ATP-binding cassette sub-family F member 2-like protein. (623 aa)

Predicted Functional Partners:

A0A482XJM1

0.912

A0A482XJT7

0.912

A0A482XDQ3

0.908

A0A482XCX9

0.901

A0A482X597

0.900

A0A482X4X1

0.891

A0A482XB08

0.886

A0A482WG72

0.885

A0A482WZT8

0.885

A0A482XVH6

0.883

Your Current Organism:

Laodelphax striatellus

NCBI taxonomy Id: 195883
Other names: L. striatellus, Laodelphax striatella, small brown planthopper

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A482WG72	A0A482WZT8	A0A482WG72	A0A482WZT8	Uncharacterized protein; Belongs to the universal ribosomal protein uS13 family.	Uncharacterized protein.	0.999
A0A482WG72	A0A482X4X1	A0A482WG72	A0A482X4X1	Uncharacterized protein; Belongs to the universal ribosomal protein uS13 family.	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family.	0.999
A0A482WG72	A0A482X597	A0A482WG72	A0A482X597	Uncharacterized protein; Belongs to the universal ribosomal protein uS13 family.	Uncharacterized protein.	0.999
A0A482WG72	A0A482XB08	A0A482WG72	A0A482XB08	Uncharacterized protein; Belongs to the universal ribosomal protein uS13 family.	Ribosomal_L23eN domain-containing protein; Belongs to the universal ribosomal protein uL23 family.	0.999
A0A482WG72	A0A482XCX9	A0A482WG72	A0A482XCX9	Uncharacterized protein; Belongs to the universal ribosomal protein uS13 family.	Tr-type G domain-containing protein.	0.982
A0A482WG72	A0A482XDQ3	A0A482WG72	A0A482XDQ3	Uncharacterized protein; Belongs to the universal ribosomal protein uS13 family.	Uncharacterized protein; Belongs to the bacterial ribosomal protein bL20 family.	0.999
A0A482WG72	A0A482XJM1	A0A482WG72	A0A482XJM1	Uncharacterized protein; Belongs to the universal ribosomal protein uS13 family.	Uncharacterized protein.	0.914
A0A482WG72	A0A482XJT7	A0A482WG72	A0A482XJT7	Uncharacterized protein; Belongs to the universal ribosomal protein uS13 family.	ABC transporter domain-containing protein.	0.914
A0A482WG72	A0A482XVH6	A0A482WG72	A0A482XVH6	Uncharacterized protein; Belongs to the universal ribosomal protein uS13 family.	Uncharacterized protein.	0.999
A0A482WG72	ABCF2	A0A482WG72	A0A161UF68	Uncharacterized protein; Belongs to the universal ribosomal protein uS13 family.	ATP-binding cassette sub-family F member 2-like protein.	0.885
A0A482WZT8	A0A482WG72	A0A482WZT8	A0A482WG72	Uncharacterized protein.	Uncharacterized protein; Belongs to the universal ribosomal protein uS13 family.	0.999
A0A482WZT8	A0A482X4X1	A0A482WZT8	A0A482X4X1	Uncharacterized protein.	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family.	0.999
A0A482WZT8	A0A482X597	A0A482WZT8	A0A482X597	Uncharacterized protein.	Uncharacterized protein.	0.999
A0A482WZT8	A0A482XB08	A0A482WZT8	A0A482XB08	Uncharacterized protein.	Ribosomal_L23eN domain-containing protein; Belongs to the universal ribosomal protein uL23 family.	0.999
A0A482WZT8	A0A482XCX9	A0A482WZT8	A0A482XCX9	Uncharacterized protein.	Tr-type G domain-containing protein.	0.985
A0A482WZT8	A0A482XDQ3	A0A482WZT8	A0A482XDQ3	Uncharacterized protein.	Uncharacterized protein; Belongs to the bacterial ribosomal protein bL20 family.	0.998
A0A482WZT8	A0A482XJM1	A0A482WZT8	A0A482XJM1	Uncharacterized protein.	Uncharacterized protein.	0.656
A0A482WZT8	A0A482XJT7	A0A482WZT8	A0A482XJT7	Uncharacterized protein.	ABC transporter domain-containing protein.	0.656
A0A482WZT8	A0A482XVH6	A0A482WZT8	A0A482XVH6	Uncharacterized protein.	Uncharacterized protein.	0.998
A0A482WZT8	ABCF2	A0A482WZT8	A0A161UF68	Uncharacterized protein.	ATP-binding cassette sub-family F member 2-like protein.	0.885

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Network Stats

number of nodes:

11

number of edges:

36

average node degree:

6.55

avg. local clustering coefficient:

0.631

expected number of edges:

21

PPI enrichment p-value:

0.00195

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019439

Aromatic compound catabolic process

8 of 44

1.63

2.89

2.49e-09

GO:0009056

Catabolic process

9 of 136

1.19

1.57

1.11e-07

GO:0044270

Cellular nitrogen compound catabolic process

3 of 29

1.38

0.75

0.0230

GO:0046700

Heterocycle catabolic process

3 of 32

1.34

0.7

0.0278

GO:0044281

Small molecule metabolic process

11 of 523

0.69

0.65

6.89e-06

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0051537

2 iron, 2 sulfur cluster binding

4 of 9

2.02

2.05

7.01e-05

GO:0071949

FAD binding

3 of 6

2.07

1.57

0.00089

GO:0016491

Oxidoreductase activity

8 of 247

0.88

0.78

0.00029

GO:0043167

Ion binding

9 of 681

0.49

0.33

0.0247

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2554

Aromatic compound catabolic process

8 of 16

2.07

4.97

1.35e-12

CL:2556

CO dehydrogenase flavoprotein, C-terminal, and Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain

6 of 7

2.3

4.57

3.52e-10

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00230

Purine metabolism

4 of 90

1.02

0.59

0.0257

map01120

Microbial metabolism in diverse environments

6 of 236

0.78

0.48

0.0225

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01799

[2Fe-2S] binding domain

3 of 3

2.37

1.77

0.00047

PF00941

FAD binding domain in molybdopterin dehydrogenase

3 of 3

2.37

1.77

0.00047

PF00111

2Fe-2S iron-sulfur cluster binding domain

3 of 5

2.15

1.72

0.00047

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036683

CO dehydrogenase flavoprotein, C-terminal domain superfamily

4 of 4

2.37

2.53

1.44e-05

IPR005107

CO dehydrogenase flavoprotein, C-terminal

4 of 4

2.37

2.53

1.44e-05

IPR036884

[2Fe-2S]-binding domain superfamily

3 of 3

2.37

1.79

0.00044

IPR002888

[2Fe-2S]-binding

3 of 3

2.37

1.79

0.00044

IPR002346

Molybdopterin dehydrogenase, FAD-binding

3 of 3

2.37

1.79

0.00044

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01092

CO dehydrogenase flavoprotein C-terminal domain

3 of 3

2.37

2.07

0.00012

SM01008

Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain

2 of 5

1.97

0.92

0.0177

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