STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFL12674.1Thioredoxin; Belongs to the thioredoxin family. (106 aa)    
Predicted Functional Partners:
SFL37368.1
Thioredoxin reductase (NADPH).
 
 0.998
SFK71364.1
Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
    
 
 0.902
SFK90503.1
Selenophosphate synthase.
   
 0.881
fusA
Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...]
 
 
 
 0.852
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
 
  
 0.842
SFL48883.1
Arsenate reductase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
 
 0.842
SFL12632.1
Double-strand break repair protein AddB.
  
    0.774
SFL12580.1
tRNA threonylcarbamoyladenosine biosynthesis protein TsaE.
       0.772
SFL12619.1
Mannose-1-phosphate guanylyltransferase.
       0.772
SFL02824.1
Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
   0.760
Your Current Organism:
Loktanella salsilacus
NCBI taxonomy Id: 195913
Other names: Antarctic bacterium R-8904, CIP 108322, DSM 16199, JCM 21636, L. salsilacus, LMG 21507, LMG:21507, Loktanella salsilacus Van Trappen et al. 2004, NBRC 102486, Tanella salinilacus
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