node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FEN1 | PHISP_03942 | A0A3M2SXA6 | A0A3M2T5W9 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Ubiquitin-like modifier SUMO. | 0.690 |
FEN1 | PHISP_04145 | A0A3M2SXA6 | A0A3M2T6K6 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Transcription elongation factor SII. | 0.534 |
FEN1 | PHISP_04721 | A0A3M2SXA6 | A0A3M2T501 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.572 |
FEN1 | PHISP_04834 | A0A3M2SXA6 | A0A3M2T3D8 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.717 |
FEN1 | PHISP_06402 | A0A3M2SXA6 | A0A3M2SYR2 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.473 |
FEN1 | PHISP_06922 | A0A3M2SXA6 | A0A3M2SXF7 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. | 0.521 |
FEN1 | PHISP_08212 | A0A3M2SXA6 | A0A3M2STP3 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | SAP30_Sin3_bdg domain-containing protein. | 0.521 |
PHISP_00738 | PHISP_03096 | A0A3M2TF38 | A0A3M2T869 | SUMO activating enzyme. | Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. | 0.987 |
PHISP_00738 | PHISP_03942 | A0A3M2TF38 | A0A3M2T5W9 | SUMO activating enzyme. | Ubiquitin-like modifier SUMO. | 0.989 |
PHISP_00738 | PHISP_06402 | A0A3M2TF38 | A0A3M2SYR2 | SUMO activating enzyme. | Uncharacterized protein. | 0.534 |
PHISP_00738 | PHISP_06755 | A0A3M2TF38 | A0A3M2SXR2 | SUMO activating enzyme. | Ubiquitin-activating enzyme E1-like; Belongs to the ubiquitin-activating E1 family. | 0.999 |
PHISP_03096 | PHISP_00738 | A0A3M2T869 | A0A3M2TF38 | Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. | SUMO activating enzyme. | 0.987 |
PHISP_03096 | PHISP_03942 | A0A3M2T869 | A0A3M2T5W9 | Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin-like modifier SUMO. | 0.999 |
PHISP_03096 | PHISP_06402 | A0A3M2T869 | A0A3M2SYR2 | Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. | Uncharacterized protein. | 0.756 |
PHISP_03096 | PHISP_06755 | A0A3M2T869 | A0A3M2SXR2 | Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin-activating enzyme E1-like; Belongs to the ubiquitin-activating E1 family. | 0.996 |
PHISP_03942 | FEN1 | A0A3M2T5W9 | A0A3M2SXA6 | Ubiquitin-like modifier SUMO. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.690 |
PHISP_03942 | PHISP_00738 | A0A3M2T5W9 | A0A3M2TF38 | Ubiquitin-like modifier SUMO. | SUMO activating enzyme. | 0.989 |
PHISP_03942 | PHISP_03096 | A0A3M2T5W9 | A0A3M2T869 | Ubiquitin-like modifier SUMO. | Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. | 0.999 |
PHISP_03942 | PHISP_04721 | A0A3M2T5W9 | A0A3M2T501 | Ubiquitin-like modifier SUMO. | Uncharacterized protein. | 0.758 |
PHISP_03942 | PHISP_04834 | A0A3M2T5W9 | A0A3M2T3D8 | Ubiquitin-like modifier SUMO. | Uncharacterized protein. | 0.707 |