STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHISP_05696Actin; Belongs to the actin family. (381 aa)    
Predicted Functional Partners:
PHISP_04179
Uncharacterized protein.
    
 0.957
PHISP_04596
Actin protein RO7; Belongs to the actin family.
    
 0.948
PHISP_03902
Uncharacterized protein; Belongs to the actin family.
  
 
0.947
PHISP_01744
Heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.944
PHISP_01699
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
 0.943
PHISP_04941
Dynactin.
    
 0.941
PHISP_06269
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
  
 
0.939
PHISP_00619
Arp2 3 complex; Belongs to the actin family.
   
0.937
PHISP_03436
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 0.936
PHISP_03247
Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family.
    
 0.936
Your Current Organism:
Phialosimplex sp. HF37
NCBI taxonomy Id: 1960876
Other names: P. sp. HF37
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.