PHISP_04639 protein (Phialosimplex sp. HF37)

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Predicted Interactions

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PHISP_04639

P-type ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (948 aa)

Predicted Functional Partners:

PHISP_07042

0.608

PHISP_03939

0.607

PHISP_08560

0.553

PHISP_03711

0.553

PHISP_03710

0.553

PHISP_04391

0.489

PHISP_04826

0.474

PHISP_04827

0.474

PHISP_08816

0.464

PHISP_08587

0.464

Your Current Organism:

Phialosimplex sp. HF37

NCBI taxonomy Id: 1960876
Other names: P. sp. HF37

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PHISP_03710	PHISP_03711	A0A3M2T7Q9	A0A3M2T6S0	SWIRM domain-containing protein.	LEM3 CDC50 family protein; Belongs to the CDC50/LEM3 family.	0.654
PHISP_03710	PHISP_03939	A0A3M2T7Q9	A0A3M2T5U4	SWIRM domain-containing protein.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.553
PHISP_03710	PHISP_04639	A0A3M2T7Q9	A0A3M2T3U0	SWIRM domain-containing protein.	P-type ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	0.553
PHISP_03710	PHISP_07042	A0A3M2T7Q9	A0A3M2SY97	SWIRM domain-containing protein.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.553
PHISP_03711	PHISP_03710	A0A3M2T6S0	A0A3M2T7Q9	LEM3 CDC50 family protein; Belongs to the CDC50/LEM3 family.	SWIRM domain-containing protein.	0.654
PHISP_03711	PHISP_03939	A0A3M2T6S0	A0A3M2T5U4	LEM3 CDC50 family protein; Belongs to the CDC50/LEM3 family.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.553
PHISP_03711	PHISP_04639	A0A3M2T6S0	A0A3M2T3U0	LEM3 CDC50 family protein; Belongs to the CDC50/LEM3 family.	P-type ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	0.553
PHISP_03711	PHISP_07042	A0A3M2T6S0	A0A3M2SY97	LEM3 CDC50 family protein; Belongs to the CDC50/LEM3 family.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.553
PHISP_03939	PHISP_03710	A0A3M2T5U4	A0A3M2T7Q9	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	SWIRM domain-containing protein.	0.553
PHISP_03939	PHISP_03711	A0A3M2T5U4	A0A3M2T6S0	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	LEM3 CDC50 family protein; Belongs to the CDC50/LEM3 family.	0.553
PHISP_03939	PHISP_04391	A0A3M2T5U4	A0A3M2T4K2	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.550
PHISP_03939	PHISP_04639	A0A3M2T5U4	A0A3M2T3U0	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	P-type ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	0.607
PHISP_03939	PHISP_08560	A0A3M2T5U4	A0A3M2SSM9	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Uncharacterized protein.	0.553
PHISP_03939	PHISP_08587	A0A3M2T5U4	A0A3M2SSK9	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Uncharacterized protein.	0.464
PHISP_03939	PHISP_08816	A0A3M2T5U4	A0A3M2SQF2	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	P-type ATPase.	0.464
PHISP_04391	PHISP_03939	A0A3M2T4K2	A0A3M2T5U4	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.550
PHISP_04391	PHISP_04639	A0A3M2T4K2	A0A3M2T3U0	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	P-type ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	0.489
PHISP_04391	PHISP_04826	A0A3M2T4K2	A0A3M2T3C6	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Uncharacterized protein.	0.731
PHISP_04391	PHISP_04827	A0A3M2T4K2	A0A3M2T3F1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Uncharacterized protein.	0.731
PHISP_04391	PHISP_07042	A0A3M2T4K2	A0A3M2SY97	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.550

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Network Stats

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006935

Chemotaxis

5 of 15

2.05

3.01

3.93e-07

GO:0007165

Signal transduction

8 of 82

1.51

2.43

1.81e-08

GO:0000160

Phosphorelay signal transduction system

5 of 60

1.45

1.53

8.76e-05

GO:0050896

Response to stimulus

9 of 335

0.95

1.02

4.05e-06

GO:0036211

Protein modification process

4 of 94

1.15

0.76

0.0107

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0050568

Protein-glutamine glutaminase activity

2 of 2

2.53

0.8

0.0349

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3981

CheW-like domain, and Protein-glutamine glutaminase activity

6 of 7

2.46

5.32

2.00e-11

CL:3894

Signal transduction, and EAL domain

11 of 57

1.81

5.02

2.85e-17

CL:3972

Bacterial chemotaxis

7 of 17

2.14

4.94

6.11e-12

CL:3895

Phosphorelay signal transduction system, and Diguanylate cyclase

4 of 38

1.55

1.47

0.00033

CL:3943

Diguanylate cyclase, and HD-GYP domain

2 of 11

1.78

0.72

0.0416

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02030

Bacterial chemotaxis

8 of 34

1.9

4.36

2.68e-12

map02020

Two-component system

8 of 250

1.03

1.13

4.22e-06

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0597

Phosphoprotein

5 of 46

1.56

1.76

3.81e-05

KW-0145

Chemotaxis

2 of 3

2.35

1.12

0.0086

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036061

CheW-like domain superfamily

3 of 3

2.53

1.74

0.00060

IPR002545

CheW-like domain

3 of 3

2.53

1.74

0.00060

IPR011006

CheY-like superfamily

4 of 30

1.65

1.38

0.00097

IPR001789

Signal transduction response regulator, receiver domain

4 of 30

1.65

1.38

0.00097

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00260

Two component signalling adaptor domain

3 of 3

2.53

2.31

4.84e-05

SM00448

cheY-homologous receiver domain

4 of 30

1.65

1.7

0.00012

SM00065

Domain present in phytochromes and cGMP-specific phosphodiesterases.

2 of 6

2.05

1.07

0.0092

SM00267

Diguanylate cyclase

2 of 8

1.92

1.01

0.0111

SM00086

Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)

2 of 11

1.78

0.92

0.0153

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