STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHISP_03836Coronin; Belongs to the WD repeat coronin family. (621 aa)    
Predicted Functional Partners:
PHISP_04376
Riboflavin synthase.
  
 
 0.936
PHISP_02493
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
 0.883
PHISP_06269
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 
 0.870
PHISP_01699
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
 0.828
PHISP_05284
GTP cyclohydrolase II.
  
 0.823
PHISP_04626
GTP cyclohydrolase.
  
 0.823
PHISP_02081
3,4-dihydroxy-2-butanone 4-phosphate synthase.
  
 0.823
PHISP_07551
Dihydrofolate reductase.
    
 0.817
PHISP_03344
Thymidylate synthase.
    
 0.807
PHISP_03347
Phosphopantothenoylcysteine decarboxylase.
    
 0.807
Your Current Organism:
Phialosimplex sp. HF37
NCBI taxonomy Id: 1960876
Other names: P. sp. HF37
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.