PHISP_03573 protein (Phialosimplex sp. HF37)

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

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[Homology]

Score

PHISP_03573

U3 small nucleolar RNA-associated protein 22. (1109 aa)

Predicted Functional Partners:

PHISP_06770

0.999

PHISP_06650

0.999

PHISP_05552

0.999

PHISP_05356

0.999

PHISP_05009

0.999

PHISP_04952

0.999

PHISP_04287

0.999

PHISP_03421

0.999

PHISP_03182

0.999

PHISP_01092

0.999

Your Current Organism:

Phialosimplex sp. HF37

NCBI taxonomy Id: 1960876
Other names: P. sp. HF37

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PHISP_01092	PHISP_03182	A0A3M2TE47	A0A3M2T816	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.998
PHISP_01092	PHISP_03421	A0A3M2TE47	A0A3M2T7E6	WD_REPEATS_REGION domain-containing protein.	DOM34-interacting protein.	0.999
PHISP_01092	PHISP_03573	A0A3M2TE47	A0A3M2T6V1	WD_REPEATS_REGION domain-containing protein.	U3 small nucleolar RNA-associated protein 22.	0.999
PHISP_01092	PHISP_04287	A0A3M2TE47	A0A3M2T687	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.999
PHISP_01092	PHISP_04952	A0A3M2TE47	A0A3M2T4A1	WD_REPEATS_REGION domain-containing protein.	BP28CT domain-containing protein.	0.999
PHISP_01092	PHISP_05009	A0A3M2TE47	A0A3M2T444	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.999
PHISP_01092	PHISP_05356	A0A3M2TE47	A0A3M2T1V4	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.997
PHISP_01092	PHISP_05552	A0A3M2TE47	A0A3M2T186	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.998
PHISP_01092	PHISP_06650	A0A3M2TE47	A0A3M2SYQ4	WD_REPEATS_REGION domain-containing protein.	Nucleolar complex protein 14.	0.995
PHISP_01092	PHISP_06770	A0A3M2TE47	A0A3M2SY27	WD_REPEATS_REGION domain-containing protein.	Periodic tryptophan protein 2.	0.999
PHISP_03182	PHISP_01092	A0A3M2T816	A0A3M2TE47	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.998
PHISP_03182	PHISP_03421	A0A3M2T816	A0A3M2T7E6	Uncharacterized protein.	DOM34-interacting protein.	0.998
PHISP_03182	PHISP_03573	A0A3M2T816	A0A3M2T6V1	Uncharacterized protein.	U3 small nucleolar RNA-associated protein 22.	0.999
PHISP_03182	PHISP_04287	A0A3M2T816	A0A3M2T687	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.999
PHISP_03182	PHISP_04952	A0A3M2T816	A0A3M2T4A1	Uncharacterized protein.	BP28CT domain-containing protein.	0.999
PHISP_03182	PHISP_05009	A0A3M2T816	A0A3M2T444	Uncharacterized protein.	Uncharacterized protein.	0.999
PHISP_03182	PHISP_05356	A0A3M2T816	A0A3M2T1V4	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.999
PHISP_03182	PHISP_05552	A0A3M2T816	A0A3M2T186	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.999
PHISP_03182	PHISP_06650	A0A3M2T816	A0A3M2SYQ4	Uncharacterized protein.	Nucleolar complex protein 14.	0.995
PHISP_03182	PHISP_06770	A0A3M2T816	A0A3M2SY27	Uncharacterized protein.	Periodic tryptophan protein 2.	0.999

page 1 of 6

Network Stats

number of nodes:

11

number of edges:

50

average node degree:

9.09

avg. local clustering coefficient:

0.889

expected number of edges:

13

PPI enrichment p-value:

3.55e-15

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:1901071

Glucosamine-containing compound metabolic process

4 of 58

1.88

1.54

0.00073

GO:0034221

Fungal-type cell wall chitin biosynthetic process

2 of 3

2.87

1.13

0.0092

GO:0006048

UDP-N-acetylglucosamine biosynthetic process

2 of 4

2.74

1.1

0.0103

GO:0006046

N-acetylglucosamine catabolic process

2 of 4

2.74

1.1

0.0103

GO:0006596

Polyamine biosynthetic process

2 of 5

2.64

1.09

0.0103

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0047419

N-acetylgalactosamine-6-phosphate deacetylase activity

2 of 2

3.04

1.19

0.0073

GO:0008448

N-acetylglucosamine-6-phosphate deacetylase activity

2 of 2

3.04

1.19

0.0073

GO:0003824

Catalytic activity

11 of 5072

0.38

0.27

0.0382

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:15182

Synthesis of UDP-N-acetyl-glucosamine, and Glucosamine catabolic process

5 of 8

2.84

4.94

5.87e-10

CL:18181

Melatonin metabolic process, and Staurosporine biosynthesis

3 of 5

2.82

2.66

1.34e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00520

Amino sugar and nucleotide sugar metabolism

5 of 153

1.56

1.82

2.37e-05

map01100

Metabolic pathways

11 of 3788

0.5

0.43

0.00022

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-446210

Synthesis of UDP-N-acetyl-glucosamine

5 of 7

2.9

5.26

1.58e-10

MAP-446219

Synthesis of substrates in N-glycan biosythesis

5 of 22

2.4

4.09

7.99e-09

MAP-446193

Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein

5 of 38

2.16

3.46

6.31e-08

MAP-446203

Asparagine N-linked glycosylation

5 of 161

1.53

1.71

4.62e-05

MAP-351202

Metabolism of polyamines

2 of 14

2.2

0.96

0.0168

(more ...)

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR003764

N-acetylglucosamine-6-phosphate deacetylase

2 of 2

3.04

1.04

0.0136

IPR017932

Glutamine amidotransferase type 2 domain

2 of 6

2.56

0.83

0.0316

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