PHISP_01169 protein (Phialosimplex sp. HF37)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

PHISP_01169

2OG-FeII_Oxy_2 domain-containing protein. (202 aa)

Predicted Functional Partners:

PHISP_01170

0.902

PHISP_07221

0.731

PHISP_05924

0.731

PHISP_02203

0.731

PHISP_02166

0.725

PHISP_02046

0.725

PHISP_02167

0.725

PHISP_04245

0.693

PHISP_04715

0.663

PHISP_04714

0.663

Your Current Organism:

Phialosimplex sp. HF37

NCBI taxonomy Id: 1960876
Other names: P. sp. HF37

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PHISP_01169	PHISP_01170	A0A3M2TEZ8	A0A3M2TDV3	2OG-FeII_Oxy_2 domain-containing protein.	Uncharacterized protein.	0.902
PHISP_01169	PHISP_02046	A0A3M2TEZ8	A0A3M2TBB2	2OG-FeII_Oxy_2 domain-containing protein.	Uncharacterized protein.	0.725
PHISP_01169	PHISP_02166	A0A3M2TEZ8	A0A3M2TB04	2OG-FeII_Oxy_2 domain-containing protein.	Uncharacterized protein.	0.725
PHISP_01169	PHISP_02167	A0A3M2TEZ8	A0A3M2TBB3	2OG-FeII_Oxy_2 domain-containing protein.	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	0.725
PHISP_01169	PHISP_02203	A0A3M2TEZ8	A0A3M2TB07	2OG-FeII_Oxy_2 domain-containing protein.	Pyridoxal-phosphate dependent enzyme.	0.731
PHISP_01169	PHISP_04245	A0A3M2TEZ8	A0A3M2T529	2OG-FeII_Oxy_2 domain-containing protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.693
PHISP_01169	PHISP_04714	A0A3M2TEZ8	A0A3M2T414	2OG-FeII_Oxy_2 domain-containing protein.	Pyruvate kinase.	0.663
PHISP_01169	PHISP_04715	A0A3M2TEZ8	A0A3M2T3K2	2OG-FeII_Oxy_2 domain-containing protein.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.663
PHISP_01169	PHISP_05924	A0A3M2TEZ8	A0A3M2T0C7	2OG-FeII_Oxy_2 domain-containing protein.	Tryptophan synthase.	0.731
PHISP_01169	PHISP_07221	A0A3M2TEZ8	A0A3M2SWJ0	2OG-FeII_Oxy_2 domain-containing protein.	Tryptophan synthase.	0.731
PHISP_01170	PHISP_01169	A0A3M2TDV3	A0A3M2TEZ8	Uncharacterized protein.	2OG-FeII_Oxy_2 domain-containing protein.	0.902
PHISP_01170	PHISP_02046	A0A3M2TDV3	A0A3M2TBB2	Uncharacterized protein.	Uncharacterized protein.	0.725
PHISP_01170	PHISP_02166	A0A3M2TDV3	A0A3M2TB04	Uncharacterized protein.	Uncharacterized protein.	0.725
PHISP_01170	PHISP_02167	A0A3M2TDV3	A0A3M2TBB3	Uncharacterized protein.	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	0.725
PHISP_01170	PHISP_02203	A0A3M2TDV3	A0A3M2TB07	Uncharacterized protein.	Pyridoxal-phosphate dependent enzyme.	0.731
PHISP_01170	PHISP_04245	A0A3M2TDV3	A0A3M2T529	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.693
PHISP_01170	PHISP_04714	A0A3M2TDV3	A0A3M2T414	Uncharacterized protein.	Pyruvate kinase.	0.663
PHISP_01170	PHISP_04715	A0A3M2TDV3	A0A3M2T3K2	Uncharacterized protein.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.663
PHISP_01170	PHISP_05924	A0A3M2TDV3	A0A3M2T0C7	Uncharacterized protein.	Tryptophan synthase.	0.731
PHISP_01170	PHISP_07221	A0A3M2TDV3	A0A3M2SWJ0	Uncharacterized protein.	Tryptophan synthase.	0.731

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Network Stats

number of nodes:

11

number of edges:

43

average node degree:

7.82

avg. local clustering coefficient:

0.869

expected number of edges:

10

PPI enrichment p-value:

2.75e-14

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031175

Neuron projection development

2 of 4

2.74

0.79

0.0378

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031386

Protein tag

4 of 18

2.39

2.82

3.90e-06

GO:0031625

Ubiquitin protein ligase binding

4 of 26

2.23

2.61

7.28e-06

GO:0019899

Enzyme binding

5 of 145

1.58

1.77

4.30e-05

GO:0003735

Structural constituent of ribosome

4 of 147

1.48

1.16

0.0021

GO:0005515

Protein binding

6 of 894

0.87

0.58

0.0114

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042995

Cell projection

3 of 66

1.7

0.84

0.0217

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:6977

Cytosolic ribosome, and GTP hydrolysis and joining of the 60S ribosomal subunit

4 of 93

1.68

1.25

0.0022

CL:6282

Mixed, incl. P-type divalent copper transporter activity, and Glucose-methanol-choline oxidoreductase, N-terminal

2 of 21

2.02

0.83

0.0279

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04120

Ubiquitin mediated proteolysis

5 of 119

1.67

2.12

6.52e-06

map03010

Ribosome

4 of 162

1.44

1.27

0.00075

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-73864

RNA Polymerase I Transcription

3 of 34

1.99

1.28

0.0033

MAP-73854

RNA Polymerase I Promoter Clearance

3 of 34

1.99

1.28

0.0033

MAP-73772

RNA Polymerase I Promoter Escape

3 of 32

2.02

1.28

0.0033

MAP-9646399

Aggrephagy

2 of 15

2.17

0.88

0.0232

MAP-5610787

Hedgehog off state

2 of 18

2.09

0.85

0.0259

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00213

Ubiquitin homologues

2 of 18

2.09

0.73

0.0443

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