node1 | node2 | node1 annotation | node2 annotation | score |
A0A136ILI4 | A0A136IM53 | Carboxyl transferase. | Pyruvate carboxyltransferase domain-containing protein; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.836 |
A0A136ILI4 | A0A136J1B3 | Carboxyl transferase. | SCP2 sterol-binding domain-containing protein. | 0.848 |
A0A136ILI4 | A0A136J2N3 | Carboxyl transferase. | Thiolase, N-terminal domain-domain-containing protein; Belongs to the thiolase-like superfamily. Thiolase family. | 0.697 |
A0A136ILI4 | A0A136J5I7 | Carboxyl transferase. | Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.697 |
A0A136IM53 | A0A136ILI4 | Pyruvate carboxyltransferase domain-containing protein; Belongs to the enoyl-CoA hydratase/isomerase family. | Carboxyl transferase. | 0.836 |
A0A136IM53 | A0A136IN84 | Pyruvate carboxyltransferase domain-containing protein; Belongs to the enoyl-CoA hydratase/isomerase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.824 |
A0A136IM53 | A0A136IRS8 | Pyruvate carboxyltransferase domain-containing protein; Belongs to the enoyl-CoA hydratase/isomerase family. | Uncharacterized protein. | 0.853 |
A0A136IM53 | A0A136IS94 | Pyruvate carboxyltransferase domain-containing protein; Belongs to the enoyl-CoA hydratase/isomerase family. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.819 |
A0A136IM53 | A0A136IWQ1 | Pyruvate carboxyltransferase domain-containing protein; Belongs to the enoyl-CoA hydratase/isomerase family. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.819 |
A0A136IM53 | A0A136J1B3 | Pyruvate carboxyltransferase domain-containing protein; Belongs to the enoyl-CoA hydratase/isomerase family. | SCP2 sterol-binding domain-containing protein. | 0.826 |
A0A136IM53 | A0A136J2N3 | Pyruvate carboxyltransferase domain-containing protein; Belongs to the enoyl-CoA hydratase/isomerase family. | Thiolase, N-terminal domain-domain-containing protein; Belongs to the thiolase-like superfamily. Thiolase family. | 0.820 |
A0A136IM53 | A0A136J508 | Pyruvate carboxyltransferase domain-containing protein; Belongs to the enoyl-CoA hydratase/isomerase family. | 3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.853 |
A0A136IM53 | A0A136J5I7 | Pyruvate carboxyltransferase domain-containing protein; Belongs to the enoyl-CoA hydratase/isomerase family. | Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.820 |
A0A136IM53 | A0A136JIC3 | Pyruvate carboxyltransferase domain-containing protein; Belongs to the enoyl-CoA hydratase/isomerase family. | Acetolactate synthase small subunit. | 0.842 |
A0A136IN84 | A0A136IM53 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Pyruvate carboxyltransferase domain-containing protein; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.824 |
A0A136IN84 | A0A136IS94 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.835 |
A0A136IN84 | A0A136IWQ1 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.835 |
A0A136IN84 | A0A136J1B3 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | SCP2 sterol-binding domain-containing protein. | 0.867 |
A0A136IN84 | A0A136J2N3 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Thiolase, N-terminal domain-domain-containing protein; Belongs to the thiolase-like superfamily. Thiolase family. | 0.986 |
A0A136IN84 | A0A136J5I7 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.984 |