STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A136IRU5SH3 domain-containing protein. (434 aa)    
Predicted Functional Partners:
A0A136JA15
Uncharacterized protein.
   
 0.944
A0A136IXP3
F-BAR domain-containing protein.
    
 0.800
A0A136J2S2
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
     
 0.730
A0A136J0W9
DUF2013 domain-containing protein.
    
 
 0.682
A0A136J4J6
WH2 domain-containing protein.
    
 0.643
A0A136IRW8
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 0.629
A0A136JAD4
SH3 domain-containing protein.
    
 0.628
A0A136JDY0
Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
     
 0.624
A0A136IJ23
Uncharacterized protein.
    
  0.622
A0A136JHV0
Non-specific serine/threonine protein kinase.
    
  0.622
Your Current Organism:
Microdochium bolleyi
NCBI taxonomy Id: 196109
Other names: M. bolleyi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.