STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAN2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1190 aa)    
Predicted Functional Partners:
A0A136IWW3
PAB-dependent poly(A)-specific ribonuclease subunit PAN3.
  
 
 0.999
A0A136IXZ7
Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.
    
 0.977
A0A136INQ1
Uncharacterized protein.
    
 0.921
A0A136IVZ4
Uncharacterized protein.
    
 0.921
A0A136JFL9
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.818
A0A136JFN5
Mysoin-binding motif of peroxisomes-domain-containing protein.
  
 0.818
A0A136J625
Endonuclease/exonuclease/phosphatase.
    
 
 0.760
A0A136JEL7
ATP-dependent RNA helicase eIF4A; Belongs to the DEAD box helicase family.
   
 0.745
A0A136J3N4
Ribonuclease H-like domain-containing protein.
   
 0.727
A0A136J8B0
DEAD/DEAH box helicase; Belongs to the DEAD box helicase family.
   
  0.706
Your Current Organism:
Microdochium bolleyi
NCBI taxonomy Id: 196109
Other names: M. bolleyi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.