node1 | node2 | node1 annotation | node2 annotation | score |
A0A136IM04 | A0A136IWP8 | Tyrosyl-DNA phosphodiesterase. | Ubiquitin-related domain-containing protein. | 0.561 |
A0A136IM04 | A0A136J2U5 | Tyrosyl-DNA phosphodiesterase. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.931 |
A0A136IM04 | A0A136JEQ4 | Tyrosyl-DNA phosphodiesterase. | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | 0.572 |
A0A136IM04 | A0A136JFB0 | Tyrosyl-DNA phosphodiesterase. | ERCC4 domain-containing protein. | 0.680 |
A0A136IRV8 | A0A136IWP8 | Ubiquitin carrier protein; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin-related domain-containing protein. | 0.999 |
A0A136IRV8 | A0A136IZ29 | Ubiquitin carrier protein; Belongs to the ubiquitin-conjugating enzyme family. | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. | 0.514 |
A0A136IRV8 | A0A136J2U5 | Ubiquitin carrier protein; Belongs to the ubiquitin-conjugating enzyme family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.870 |
A0A136IRV8 | A0A136J6P8 | Ubiquitin carrier protein; Belongs to the ubiquitin-conjugating enzyme family. | Ribonuclease H-like domain-containing protein. | 0.801 |
A0A136IRV8 | A0A136JEQ4 | Ubiquitin carrier protein; Belongs to the ubiquitin-conjugating enzyme family. | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | 0.862 |
A0A136IRV8 | A0A136JFB0 | Ubiquitin carrier protein; Belongs to the ubiquitin-conjugating enzyme family. | ERCC4 domain-containing protein. | 0.556 |
A0A136IWP8 | A0A136IM04 | Ubiquitin-related domain-containing protein. | Tyrosyl-DNA phosphodiesterase. | 0.561 |
A0A136IWP8 | A0A136IRV8 | Ubiquitin-related domain-containing protein. | Ubiquitin carrier protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.999 |
A0A136IWP8 | A0A136J2U5 | Ubiquitin-related domain-containing protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.882 |
A0A136IWP8 | A0A136J6P8 | Ubiquitin-related domain-containing protein. | Ribonuclease H-like domain-containing protein. | 0.849 |
A0A136IWP8 | A0A136JBQ2 | Ubiquitin-related domain-containing protein. | Tyrosyl-DNA phosphodiesterase I. | 0.455 |
A0A136IWP8 | A0A136JEQ4 | Ubiquitin-related domain-containing protein. | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | 0.912 |
A0A136IWP8 | A0A136JFB0 | Ubiquitin-related domain-containing protein. | ERCC4 domain-containing protein. | 0.628 |
A0A136IZ29 | A0A136IRV8 | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. | Ubiquitin carrier protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.514 |
A0A136IZ29 | A0A136J2U5 | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.798 |
A0A136IZ29 | A0A136J6P8 | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. | Ribonuclease H-like domain-containing protein. | 0.992 |