STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A136J704Vps5 C terminal like-domain-containing protein. (582 aa)    
Predicted Functional Partners:
A0A136J3L5
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 0.986
A0A136J5I6
Vacuolar protein sorting-associated protein 26.
   
 0.984
A0A136JJ25
Vacuolar protein sorting-associated protein 29; Belongs to the VPS29 family.
   
 0.984
A0A136J5M2
Vacuolar protein sorting-associated protein 17; Plays a role in vesicular protein sorting. Belongs to the VPS17 family.
    
0.956
A0A136J7W9
RmlD_sub_bind domain-containing protein.
 
  
   0.905
A0A136J2S2
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
    
 0.779
A0A136J5H0
Sortilin; Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.
    
 0.773
MED11
Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
 
      0.763
A0A136JCN4
Mannose-6-phosphate receptor binding domain-containing protein.
    
 0.761
A0A136JAN4
ANTH domain-domain-containing protein.
   
 0.752
Your Current Organism:
Microdochium bolleyi
NCBI taxonomy Id: 196109
Other names: M. bolleyi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.