STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A136JGY1Indoleamine 2,3-dioxygenase. (470 aa)    
Predicted Functional Partners:
BNA5
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.
   
 0.890
A0A136J799
Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
   
 
 0.806
A0A136JD19
Indoleamine 2,3-dioxygenase.
  
  
 
0.790
A0A136J2Z0
Putative L-kynurenine/alpha-aminoadipate aminotransferase.
     
 0.765
A0A136INB4
N-acetyltransferase domain-containing protein.
     
 0.740
A0A136IZN2
Pyridoxal phosphate-dependent transferase.
     
 0.736
A0A136INY5
Flavin-containing amine oxidoreductase-domain containing protein.
     
 0.731
A0A136IJ65
Pyridoxal phosphate-dependent transferase.
   
 
  0.727
A0A136JDZ5
Pyridoxal phosphate-dependent transferase.
   
 
  0.727
A0A136IPE9
Uncharacterized protein.
     
 0.641
Your Current Organism:
Microdochium bolleyi
NCBI taxonomy Id: 196109
Other names: M. bolleyi
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