OQY72717.1 protein (Ignavibacteriales bacterium UTCHB2)

Nodes:

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second shell of interactors

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Edges:

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

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Coexpression

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[Homology]

Score

OQY72717.1

Hypothetical protein. (566 aa)

Predicted Functional Partners:

OQY71901.1

0.932

OQY72904.1

0.868

OQY70513.1

0.825

OQY72186.1

0.800

OQY73683.1

0.775

OQY71934.1

0.775

OQY71278.1

0.775

OQY70062.1

0.768

OQY73004.1

0.759

OQY69591.1

0.759

Your Current Organism:

Ignavibacteriales bacterium UTCHB2

NCBI taxonomy Id: 1961105
Other names: I. bacterium UTCHB2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OQY69591.1	OQY70062.1	B6D44_17540	B6D44_16570	alanine--tRNA ligase.	Hypothetical protein.	0.549
OQY69591.1	OQY72717.1	B6D44_17540	B6D44_09525	alanine--tRNA ligase.	Hypothetical protein.	0.759
OQY70062.1	OQY69591.1	B6D44_16570	B6D44_17540	Hypothetical protein.	alanine--tRNA ligase.	0.549
OQY70062.1	OQY70513.1	B6D44_16570	B6D44_15665	Hypothetical protein.	Molecular chaperone HtpG.	0.783
OQY70062.1	OQY71278.1	B6D44_16570	B6D44_13290	Hypothetical protein.	Hypothetical protein.	0.487
OQY70062.1	OQY71901.1	B6D44_16570	B6D44_11260	Hypothetical protein.	Hypothetical protein.	0.553
OQY70062.1	OQY71934.1	B6D44_16570	B6D44_11425	Hypothetical protein.	Hypothetical protein.	0.487
OQY70062.1	OQY72186.1	B6D44_16570	B6D44_10585	Hypothetical protein.	Molecular chaperone DnaK.	0.976
OQY70062.1	OQY72717.1	B6D44_16570	B6D44_09525	Hypothetical protein.	Hypothetical protein.	0.768
OQY70062.1	OQY73004.1	B6D44_16570	B6D44_08470	Hypothetical protein.	Hypothetical protein.	0.549
OQY70062.1	OQY73683.1	B6D44_16570	B6D44_06650	Hypothetical protein.	Hypothetical protein.	0.487
OQY70513.1	OQY70062.1	B6D44_15665	B6D44_16570	Molecular chaperone HtpG.	Hypothetical protein.	0.783
OQY70513.1	OQY71901.1	B6D44_15665	B6D44_11260	Molecular chaperone HtpG.	Hypothetical protein.	0.670
OQY70513.1	OQY72186.1	B6D44_15665	B6D44_10585	Molecular chaperone HtpG.	Molecular chaperone DnaK.	0.999
OQY70513.1	OQY72717.1	B6D44_15665	B6D44_09525	Molecular chaperone HtpG.	Hypothetical protein.	0.825
OQY71278.1	OQY70062.1	B6D44_13290	B6D44_16570	Hypothetical protein.	Hypothetical protein.	0.487
OQY71278.1	OQY71901.1	B6D44_13290	B6D44_11260	Hypothetical protein.	Hypothetical protein.	0.999
OQY71278.1	OQY71934.1	B6D44_13290	B6D44_11425	Hypothetical protein.	Hypothetical protein.	0.999
OQY71278.1	OQY72186.1	B6D44_13290	B6D44_10585	Hypothetical protein.	Molecular chaperone DnaK.	0.500
OQY71278.1	OQY72717.1	B6D44_13290	B6D44_09525	Hypothetical protein.	Hypothetical protein.	0.775

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

35

average node degree:

6.36

avg. local clustering coefficient:

0.855

expected number of edges:

12

PPI enrichment p-value:

2.01e-08

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006094

Gluconeogenesis

4 of 12

1.79

1.6

0.00041

GO:0006566

Threonine metabolic process

2 of 5

1.87

0.79

0.0315

GO:0044283

Small molecule biosynthetic process

8 of 204

0.86

0.75

0.00041

GO:1901605

Alpha-amino acid metabolic process

5 of 87

1.03

0.73

0.0065

GO:0006563

L-serine metabolic process

2 of 6

1.79

0.73

0.0386

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016841

Ammonia-lyase activity

5 of 10

1.97

2.6

2.69e-06

GO:0003941

L-serine ammonia-lyase activity

4 of 5

2.17

2.49

1.11e-05

GO:0051539

4 iron, 4 sulfur cluster binding

4 of 21

1.55

1.34

0.00080

GO:0016829

Lyase activity

6 of 103

1.03

0.88

0.00088

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1262

Cysteine and methionine metabolism, and Homoserine kinase

6 of 24

1.66

2.4

6.23e-07

CL:1261

Cysteine and methionine metabolism, and Valine, leucine and isoleucine biosynthesis

7 of 39

1.52

2.22

2.71e-07

CL:1296

L-serine ammonia-lyase activity, and Homoserine kinase

3 of 5

2.04

1.67

0.00051

CL:1259

Biosynthesis of amino acids

8 of 101

1.17

1.42

1.18e-06

CL:1267

Transsulfuration, and Threonine biosynthesis

2 of 5

1.87

0.75

0.0373

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00260

Glycine, serine and threonine metabolism

8 of 32

1.66

3.22

1.68e-10

map00270

Cysteine and methionine metabolism

6 of 40

1.44

1.93

1.35e-06

map01230

Biosynthesis of amino acids

10 of 118

1.19

1.77

3.55e-10

map01200

Carbon metabolism

7 of 77

1.22

1.53

1.35e-06

map01110

Biosynthesis of secondary metabolites

10 of 317

0.77

0.76

1.90e-06

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0312

Gluconeogenesis

3 of 9

1.79

1.36

0.0016

KW-0456

Lyase

6 of 61

1.26

1.32

7.57e-05

KW-0412

Isoleucine biosynthesis

2 of 2

2.27

1.21

0.0055

KW-0004

4Fe-4S

3 of 16

1.54

1.05

0.0050

KW-0028

Amino-acid biosynthesis

5 of 60

1.19

1.02

0.0010

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF03315

Serine dehydratase beta chain

3 of 3

2.27

1.62

0.00087

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR029009

Allosteric substrate binding domain superfamily

3 of 3

2.27

1.4

0.0024

IPR005131

Serine dehydratase beta chain

3 of 3

2.27

1.4

0.0024

IPR004643

Iron-sulphur-dependent L-serine dehydratase beta subunit

3 of 3

2.27

1.4

0.0024

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