Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
crgAHypothetical protein; Involved in cell division; Belongs to the CrgA family. (152 aa)    
Predicted Functional Partners:
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
    
 
 0.869
whiA
Protein of unknown function DUF199; Involved in cell division and chromosome segregation.
      
 0.842
Noca_0021
PFAM: protein of unknown function DUF881; KEGG: pac:PPA0183 membrane spanning protein DUF881.
       0.683
Noca_3064
Cell division-specific peptidoglycan biosynthesis regulator FtsW; TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: sma:SAV6121 putative cell division protein FtsW; Belongs to the SEDS family.
     
 0.630
Noca_3069
Peptidoglycan synthetase FtsI; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: sco:SCO2090 cell division protein.
   
 
 0.605
Noca_0024
Cell elongation-specific peptidoglycan D,D-transpeptidase; PFAM: penicillin-binding protein, transpeptidase; KEGG: fal:FRAAL6753 putative penicillin-binding protein PbpA.
   
 
 0.541
ftsQ
Cell division protein FtsQ; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily.
    
 
 0.533
Noca_0027
PFAM: Forkhead-associated protein; KEGG: tfu:Tfu_3061 FHA domain protein.
  
  
 0.508
Noca_3055
PFAM: DivIVA family protein; KEGG: tfu:Tfu_1118 hypothetical protein.
      
 0.451
sepF
Protein of unknown function DUF552; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
      
 0.418
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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