Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Noca_0164PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: rha:RHA1_ro05084 probable adenylate cyclase. (371 aa)    
Predicted Functional Partners:
Noca_3492
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: sma:SAV3329 putative adenylate cyclase.
  
  
 
0.919
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.906
Noca_2392
RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
 0.903
Noca_0274
PFAM: RelA/SpoT domain protein; KEGG: lxx:Lxx23800 hypothetical protein.
     
 0.901
Noca_2189
PFAM: RelA/SpoT domain protein; KEGG: lxx:Lxx23800 hypothetical protein.
     
 0.901
moaA
GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
   
 
 0.805
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
  0.805
moaA-2
GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
   
 
 0.805
Noca_0165
PFAM: cyclic nucleotide-binding; KEGG: mmc:Mmcs_2490 cyclic nucleotide-binding protein.
 
 0.800
folE
PFAM: GTP cyclohydrolase I; KEGG: sma:SAV4667 putative GTP cyclohydrolase I.
     
  0.800
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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