STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_0171KEGG: sth:STH3328 hypothetical protein. (142 aa)    
Predicted Functional Partners:
Noca_1516
ATP-dependent DNA helicase, Rep family; PFAM: UvrD/REP helicase; HRDC domain protein; KEGG: sco:SCO5188 putative ATP-dependent DNA helicase.
  
 
 0.786
Noca_0172
PFAM: Mycobacterium tuberculosis paralogous family 11; KEGG: rha:RHA1_ro02638 hypothetical protein.
  
    0.715
Noca_0170
PFAM: prephenate dehydratase; KEGG: rpa:RPA3695 chorismate mutase/prephenate dehydratase.
  
    0.667
Noca_3464
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
  
 0.654
Noca_2495
Condensin subunit ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
 
 0.621
Noca_2862
PFAM: glycoside hydrolase, family 18; SMART: chitinase II; KEGG: dsy:DSY4848 hypothetical protein.
 
     0.606
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.544
Noca_2958
KEGG: sma:SAV2442 putative a subunit of topoisomerase IV; PFAM: DNA gyrase, subunit B domain protein; ATP-binding region, ATPase domain protein domain protein; DNA topoisomerase, type IIA, subunit B, region 2 domain protein; SMART: DNA topoisomerase II.
   
 
 0.544
Noca_0024
Cell elongation-specific peptidoglycan D,D-transpeptidase; PFAM: penicillin-binding protein, transpeptidase; KEGG: fal:FRAAL6753 putative penicillin-binding protein PbpA.
 
   
 0.541
Noca_3461
TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: fal:FRAAL1920 rod shape-determining membrane protein; cell elongation; Belongs to the SEDS family.
 
   
 0.529
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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