Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Noca_0210PFAM: alpha/beta hydrolase fold; KEGG: ttj:TTHB237 2-hydroxymuconic semialdehyde hydrolase. (279 aa)    
Predicted Functional Partners:
Noca_0209
PFAM: Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: bur:Bcep18194_B1413 acyl-CoA dehydrogenase-like.
 
  0.880
Noca_0206
PFAM: Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: nfa:nfa33590 hypothetical protein.
 
  0.811
Noca_0207
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mmc:Mmcs_1630 glyoxalase/bleomycin resistance protein/dioxygenase.
 
  
 0.810
Noca_0211
5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: rha:RHA1_ro04906 hypothetical protein.
 
  
 0.799
Noca_1649
Pyruvate carboxyltransferase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 
 0.694
Noca_2149
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 
 0.681
Noca_0208
PFAM: alpha/beta hydrolase fold; KEGG: ttj:TTHB237 2-hydroxymuconic semialdehyde hydrolase.
 
    
0.676
Noca_2150
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
  
 0.642
Noca_1650
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
  
 0.641
Noca_2055
PFAM: Hydratase/decarboxylase; KEGG: mxa:MXAN_0925 putative 4-oxalocrotonate decarboxylase.
 
  
 0.577
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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