STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_0261NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (471 aa)    
Predicted Functional Partners:
Noca_0260
TIGRFAM: NAD(P) transhydrogenase, alpha subunit; PFAM: alanine dehydrogenase/PNT domain protein; KEGG: rha:RHA1_ro02720 NAD(P) transhydrogenase alpha subunit.
 0.999
Noca_2488
TIGRFAM: alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT domain protein; KEGG: sma:SAV6507 putative L-alanine dehydrogenase; Belongs to the AlaDH/PNT family.
     0.924
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.920
nadK
NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.906
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
    
 0.905
cobB
PFAM: Silent information regulator protein Sir2; KEGG: sal:Sala_2748 silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily.
    
  0.903
Noca_1514
PFAM: NUDIX hydrolase; KEGG: tfu:Tfu_0527 conserved hypothetical protein.
     
  0.900
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.