STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_0280(S)-2-hydroxy-acid oxidase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: nfa:nfa32960 putative L-lactate dehydrogenase. (410 aa)    
Predicted Functional Partners:
Noca_4175
PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: mpa:MAP3255 pyruvate decarboxylase; Belongs to the TPP enzyme family.
 
 
 0.942
Noca_3513
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 
 0.926
Noca_3020
PFAM: pyruvate kinase; KEGG: sma:SAV6217 putative pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.925
Noca_3274
Alanine-glyoxylate aminotransferase apoenzyme; PFAM: aminotransferase, class V; KEGG: hma:rrnAC1999 aminotransferase class V.
  
 0.922
Noca_0537
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: tfu:Tfu_2674 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit.
    
 0.914
Noca_0113
Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: amino acid-binding ACT domain protein; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: tfu:Tfu_2390 malate dehydrogenase (oxaloacetate decarboxylating).
    
 0.906
Noca_0536
PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: sma:SAV4876 2-oxoglutarate ferredoxin oxidoreductase, beta subunit.
    
 0.906
Noca_1727
Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: sma:SAV2981 putative malate dehydrogenase.
    
 0.906
Noca_1993
2-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.906
Noca_2034
Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: amino acid-binding ACT domain protein; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: rha:RHA1_ro00492 malate dehydrogenase (oxaloacetate-decarboxylating).
    
 0.906
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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