STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaXDNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (678 aa)    
Predicted Functional Partners:
Noca_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 
 0.994
Noca_1888
TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta; KEGG: sco:SCO2564 putative DNA polymerase III, delta subunit.
 
 
 0.985
Noca_3810
PFAM: BRCT domain protein; Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: tfu:Tfu_0714 exonuclease.
  
 0.972
Noca_3050
KEGG: lxx:Lxx15160 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP C-terminal domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; SMART: phosphoesterase PHP domain protein.
 
 0.968
Noca_3128
DNA polymerase III, epsilon subunit; KEGG: fal:FRAAL5108 putative DNA-directed DNA polymerase; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Excinuclease ABC, C subunit domain protein; UvrB/UvrC protein; Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease.
  
 0.944
Noca_0387
TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: pac:PPA0244 DNA polymerase III delta' subunit.
  
  
 
0.925
recR
DNA replication and repair protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
 
  
 0.875
Noca_0318
Conserved hypothetical protein 103; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
  
  
 0.852
Noca_0320
KEGG: sma:SAV4558 hypothetical protein.
       0.715
dnaE2
Error-prone DNA polymerase, DnaE-like protein; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.
 
 
 0.688
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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