STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (664 aa)    
Predicted Functional Partners:
Noca_0888
KEGG: rxy:Rxyl_1676 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 0.974
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 
 0.969
Noca_0733
PFAM: Citrate synthase; KEGG: sma:SAV3859 putative citrate synthase; Belongs to the citrate synthase family.
  
 0.964
Noca_2954
Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.950
Noca_0537
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: tfu:Tfu_2674 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit.
  
 
 0.941
Noca_2092
PFAM: aldehyde dehydrogenase; KEGG: sma:SAV7177 putative aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.936
Noca_3529
PFAM: aldehyde dehydrogenase; KEGG: sco:SCO4913 putative aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.936
Noca_3634
PFAM: aldehyde dehydrogenase; KEGG: mpa:MAP2338 hypothetical protein.
  
 0.936
Noca_4626
TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: mmc:Mmcs_0348 methylmalonate-semialdehyde dehydrogenase.
  
 0.936
Noca_1371
KEGG: sma:SAV3512 putative thiolase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.935
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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