Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Noca_0347TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: sco:SCO1822 putative transmembrane transport protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (534 aa)    
Predicted Functional Partners:
Noca_0348
PFAM: protein of unknown function DUF485; KEGG: sma:SAV6453 hypothetical protein.
 
  
 0.993
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.738
Noca_0860
PFAM: AMP-dependent synthetase and ligase; KEGG: rxy:Rxyl_1704 AMP-dependent synthetase and ligase.
  
  
 0.470
Noca_0349
PFAM: major facilitator superfamily MFS_1; KEGG: bja:blr2806 nitrite extrusion protein.
       0.443
Noca_0350
Assimilatory nitrate reductase (NADH) alpha subunit apoprotein; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: fra:Francci3_0863 molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
       0.443
Noca_1406
KEGG: sma:SAV5035 hypothetical protein.
  
  
 0.441
Noca_1696
PFAM: CBS domain containing protein; KEGG: mpa:MAP2219c hypothetical protein.
  
  
 0.434
Noca_0355
PFAM: Na+/solute symporter; KEGG: sma:SAV7117 transmembrane transport protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
    
0.425
Noca_2954
Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
   
  
 0.401
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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