STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_0358Histidine kinase internal region; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase internal region; KEGG: sma:SAV7118 putative two-component system sensor kinase. (374 aa)    
Predicted Functional Partners:
Noca_0357
PFAM: response regulator receiver; LytTr DNA-binding region; KEGG: sma:SAV7115 regulatory protein.
 
 
 0.987
Noca_0356
KEGG: rha:RHA1_ro05042 hypothetical protein.
 
     0.961
Noca_0355
PFAM: Na+/solute symporter; KEGG: sma:SAV7117 transmembrane transport protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
     0.952
Noca_0359
Carbonate dehydratase; PFAM: carbonic anhydrase; KEGG: mag:amb0581 carbonic anhydrase.
       0.773
Noca_0360
PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: mpa:MAP3459 putative methyltransferase.
       0.703
Noca_0348
PFAM: protein of unknown function DUF485; KEGG: sma:SAV6453 hypothetical protein.
 
     0.444
Noca_0347
TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: sco:SCO1822 putative transmembrane transport protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
     0.425
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
       0.424
Noca_1061
Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
       0.404
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
Server load: low (26%) [HD]