node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Noca_0387 | Noca_0388 | Noca_0387 | Noca_0388 | TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: pac:PPA0244 DNA polymerase III delta' subunit. | Tripeptidyl-peptidase B, Serine peptidase, MEROPS family S33; PFAM: alpha/beta hydrolase fold; TAP domain protein; KEGG: sco:SCO3540 proteinase (secreted protein). | 0.840 |
Noca_0387 | tmk | Noca_0387 | Noca_0386 | TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: pac:PPA0244 DNA polymerase III delta' subunit. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.874 |
Noca_0388 | Noca_0387 | Noca_0388 | Noca_0387 | Tripeptidyl-peptidase B, Serine peptidase, MEROPS family S33; PFAM: alpha/beta hydrolase fold; TAP domain protein; KEGG: sco:SCO3540 proteinase (secreted protein). | TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: pac:PPA0244 DNA polymerase III delta' subunit. | 0.840 |
Noca_0388 | tmk | Noca_0388 | Noca_0386 | Tripeptidyl-peptidase B, Serine peptidase, MEROPS family S33; PFAM: alpha/beta hydrolase fold; TAP domain protein; KEGG: sco:SCO3540 proteinase (secreted protein). | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.840 |
Noca_2321 | Noca_2322 | Noca_2321 | Noca_2322 | PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: cgb:cg0397 probable 5'-nucleotidase precursor; Belongs to the 5'-nucleotidase family. | PFAM: Endonuclease/exonuclease/phosphatase; KEGG: cjk:jk1043 putative extracellular nuclease. | 0.997 |
Noca_2321 | Noca_2919 | Noca_2321 | Noca_2919 | PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: cgb:cg0397 probable 5'-nucleotidase precursor; Belongs to the 5'-nucleotidase family. | PFAM: thymidine kinase; KEGG: sco:SCO5845 putative thimidine kinase. | 0.904 |
Noca_2321 | dut | Noca_2321 | Noca_2908 | PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: cgb:cg0397 probable 5'-nucleotidase precursor; Belongs to the 5'-nucleotidase family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.900 |
Noca_2321 | guaB | Noca_2321 | Noca_3645 | PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: cgb:cg0397 probable 5'-nucleotidase precursor; Belongs to the 5'-nucleotidase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.921 |
Noca_2321 | thyA | Noca_2321 | Noca_2311 | PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: cgb:cg0397 probable 5'-nucleotidase precursor; Belongs to the 5'-nucleotidase family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.907 |
Noca_2321 | tmk | Noca_2321 | Noca_0386 | PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: cgb:cg0397 probable 5'-nucleotidase precursor; Belongs to the 5'-nucleotidase family. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.930 |
Noca_2322 | Noca_2321 | Noca_2322 | Noca_2321 | PFAM: Endonuclease/exonuclease/phosphatase; KEGG: cjk:jk1043 putative extracellular nuclease. | PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: cgb:cg0397 probable 5'-nucleotidase precursor; Belongs to the 5'-nucleotidase family. | 0.997 |
Noca_2322 | Noca_2919 | Noca_2322 | Noca_2919 | PFAM: Endonuclease/exonuclease/phosphatase; KEGG: cjk:jk1043 putative extracellular nuclease. | PFAM: thymidine kinase; KEGG: sco:SCO5845 putative thimidine kinase. | 0.921 |
Noca_2322 | dut | Noca_2322 | Noca_2908 | PFAM: Endonuclease/exonuclease/phosphatase; KEGG: cjk:jk1043 putative extracellular nuclease. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.900 |
Noca_2322 | guaB | Noca_2322 | Noca_3645 | PFAM: Endonuclease/exonuclease/phosphatase; KEGG: cjk:jk1043 putative extracellular nuclease. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.900 |
Noca_2322 | thyA | Noca_2322 | Noca_2311 | PFAM: Endonuclease/exonuclease/phosphatase; KEGG: cjk:jk1043 putative extracellular nuclease. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.900 |
Noca_2322 | tmk | Noca_2322 | Noca_0386 | PFAM: Endonuclease/exonuclease/phosphatase; KEGG: cjk:jk1043 putative extracellular nuclease. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.914 |
Noca_2919 | Noca_2321 | Noca_2919 | Noca_2321 | PFAM: thymidine kinase; KEGG: sco:SCO5845 putative thimidine kinase. | PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: cgb:cg0397 probable 5'-nucleotidase precursor; Belongs to the 5'-nucleotidase family. | 0.904 |
Noca_2919 | Noca_2322 | Noca_2919 | Noca_2322 | PFAM: thymidine kinase; KEGG: sco:SCO5845 putative thimidine kinase. | PFAM: Endonuclease/exonuclease/phosphatase; KEGG: cjk:jk1043 putative extracellular nuclease. | 0.921 |
Noca_2919 | Noca_3811 | Noca_2919 | Noca_3811 | PFAM: thymidine kinase; KEGG: sco:SCO5845 putative thimidine kinase. | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.466 |
Noca_2919 | dut | Noca_2919 | Noca_2908 | PFAM: thymidine kinase; KEGG: sco:SCO5845 putative thimidine kinase. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.979 |