Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Noca_0430PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: eli:ELI_09720 esterase. (305 aa)    
Predicted Functional Partners:
Noca_0429
PFAM: GCN5-related N-acetyltransferase; KEGG: rha:RHA1_ro06613 hypothetical protein.
       0.782
Noca_4256
PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: mpa:MAP3006c LipN.
  
     0.773
Noca_2793
PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: rha:RHA1_ro06856 possible esterase/lipase.
  
     0.561
Noca_0431
TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase; KEGG: sma:SAV1635 hypothetical protein.
       0.546
Noca_0432
RNA polymerase, sigma subunit, ECF family; PFAM: DNA gyrase C-terminal repeat, beta-propeller; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: sco:SCO2742 putative sigma factor.
       0.546
Noca_1882
PFAM: FAD dependent oxidoreductase; KEGG: nfa:nfa43490 putative monooxygenase.
  
 0.463
Noca_1335
PFAM: Rieske [2Fe-2S] domain protein; FAD dependent oxidoreductase; KEGG: mpa:MAP1672 hypothetical protein.
  
 
 0.453
nuoI
NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 
 0.434
Noca_3698
KEGG: nfa:nfa47010 putative monooxygenase.
  
 0.426
Noca_3176
PFAM: peptidase M16 domain protein; KEGG: fal:FRAAL5752 putative zinc protease; Belongs to the peptidase M16 family.
    
 
 0.407
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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