Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Noca_0449KEGG: sco:SCO3402 secreted protein. (163 aa)    
Predicted Functional Partners:
Noca_0448
KEGG: sco:SCO3401 putative hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK.
 
     0.869
Noca_0447
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
       0.842
folE
PFAM: GTP cyclohydrolase I; KEGG: sma:SAV4667 putative GTP cyclohydrolase I.
  
    0.805
Noca_0446
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
       0.801
Noca_0450
KEGG: sco:SCP2.27c putative multidomain membrane protein.
       0.781
Noca_3586
Hypothetical protein; KEGG: sma:SAV3318 putative RNA polymerase ECF-subfamily sigma factor.
  
     0.766
Noca_0299
KEGG: pac:PPA2178 hypothetical protein.
  
     0.753
Noca_4682
KEGG: sco:SCO3895 hypothetical protein.
  
     0.753
Noca_1427
KEGG: pac:PPA1688 hypothetical protein.
  
     0.737
Noca_3369
KEGG: dra:DR0603 cytidine/deoxycytidylate deaminase/NUDIX/methyltransferase domains protein.
  
     0.735
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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