Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Noca_0463KEGG: fra:Francci3_4378 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. (300 aa)    
Predicted Functional Partners:
Noca_0462
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
  
 0.999
nadA
Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
 
 
 0.999
Noca_1307
Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
   
 0.982
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
    
 0.958
Noca_0032
PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; KEGG: mka:MK0828 succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
  
 0.950
Noca_2324
PFAM: CinA domain protein; KEGG: fal:FRAAL5732 competence-inducible (CinA-like) protein; Belongs to the CinA family.
    
 0.916
Noca_1514
PFAM: NUDIX hydrolase; KEGG: tfu:Tfu_0527 conserved hypothetical protein.
     
 0.902
Noca_2321
PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: cgb:cg0397 probable 5'-nucleotidase precursor; Belongs to the 5'-nucleotidase family.
    
  0.902
Noca_1242
TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sco:SCO2843 putative N-acetylglucosamine-6-phosphate deacetylase; Belongs to the HAD-like hydrolase superfamily.
   
 
  0.901
Noca_2322
PFAM: Endonuclease/exonuclease/phosphatase; KEGG: cjk:jk1043 putative extracellular nuclease.
     
  0.900
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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