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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
moaAGTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (329 aa)    
Predicted Functional Partners:
moaC
GTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
 
 0.999
Noca_1526
PFAM: molybdopterin biosynthesis MoaE; KEGG: sma:SAV3059 putative molybdopterin biosynthesis protein E.
 
 
 0.957
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
 0.907
folE
PFAM: GTP cyclohydrolase I; KEGG: sma:SAV4667 putative GTP cyclohydrolase I.
    
  0.905
Noca_0793
TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; KEGG: sco:SCO3179 molybdenum cofactor biosynthesis protein (putative secreted protein).
 
  
 0.905
folE-2
PFAM: GTP cyclohydrolase I; KEGG: nfa:nfa31470 putative GTP cyclohydrolase I.
    
  0.905
moaA-2
GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
  
  
 
0.901
Noca_0866
PFAM: GTP cyclohydrolase II; KEGG: sma:SAV545 putative GTP cyclohydrolase II.
    
  0.900
Noca_1684
PFAM: GTP cyclohydrolase II; KEGG: sma:SAV4121 putative GTP cyclohydrolase II.
    
  0.900
Noca_0791
Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 0.896
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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