Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
Noca_0658PFAM: aldo/keto reductase; KEGG: tma:TM1297 oxidoreductase, putative. (288 aa)    
Predicted Functional Partners:
Noca_0657
PFAM: homogentisate 1,2-dioxygenase; Cupin 2, conserved barrel domain protein; KEGG: rha:RHA1_ro02311 homogentisate 1,2-dioxygenase.
  
    0.730
Noca_3933
PFAM: ExsB family protein; Haloacid dehalogenase domain protein hydrolase; PP-loop domain protein; KEGG: ade:Adeh_1542 hypothetical protein.
 
     0.590
Noca_0169
KEGG: syc:syc0382_d circadian phase modifier CpmA.
 
   
 0.576
Noca_0655
Fumarylacetoacetate hydrolase; KEGG: rha:RHA1_ro02309 probable fumarylacetoacetase; TIGRFAM: fumarylacetoacetase; PFAM: fumarylacetoacetate (FAA) hydrolase.
  
    0.545
larC
Protein of unknown function DUF111; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.
 
     0.544
Noca_0656
KEGG: rha:RHA1_ro02310 hypothetical protein.
       0.535
Noca_2622
PFAM: aldo/keto reductase; KEGG: sma:SAV6640 oxidoreductase.
  
     0.476
Noca_2000
KEGG: rxy:Rxyl_2107 hypothetical protein.
  
     0.459
Noca_2688
PFAM: aldo/keto reductase; KEGG: sco:SCO7356 oxidoreductase.
  
 
 0.438
Noca_1698
Hypothetical protein.
  
   0.408
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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