STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_0664PFAM: methyladenine glycosylase; KEGG: cef:CE2657 putative 3-methyladenine-DNA glycosylase. (197 aa)    
Predicted Functional Partners:
Noca_3300
methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
   
 0.774
Noca_3301
DNA-O6-methylguanine--protein-cysteine S-methyltransferase / DNA-3-methyladenine glycosylase II; PFAM: helix-turn-helix- domain containing protein, AraC type; HhH-GPD family protein; Ada, metal-binding domain protein; AlkA domain protein; KEGG: sco:SCO6461 putative ADA-like regulatory protein.
     
 0.594
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.576
Noca_0663
PFAM: Pirin domain protein domain protein; Pirin domain protein; KEGG: sco:SCO0468 hypothetical protein; Belongs to the pirin family.
       0.544
Noca_0467
HhH-GPD family protein; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; KEGG: sco:SCO3355 putative adenine glycosylase.
     
 0.455
Noca_0665
PFAM: ROK family protein; KEGG: rha:RHA1_ro02370 possible xylose repressor.
       0.455
Noca_0666
PFAM: Amidase; KEGG: mmc:Mmcs_1995 amidase.
       0.444
Noca_2578
PFAM: band 7 protein; KEGG: sma:SAV6482 secreted protein.
 
    0.441
Noca_0662
TIGRFAM: oxidoreductase alpha (molybdopterin) subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: rha:RHA1_ro03039 formate dehydrogenase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
       0.420
argR
Transcriptional regulator, ArgR family; Regulates arginine biosynthesis genes.
  
    0.400
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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