Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Noca_0676KEGG: rha:RHA1_ro05298 hypothetical protein. (170 aa)    
Predicted Functional Partners:
Noca_1505
Barbiturase; Responsible for the hydrolysis of barbituric acid (2,4,6- trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid; Belongs to the cyclic amide hydrolase (CyAH) family.
 
     0.776
Noca_4270
Barbiturase; Responsible for the hydrolysis of barbituric acid (2,4,6- trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid. Can also use cyanuric acid as a substrate, albeit with lower efficiency.
 
     0.775
Noca_1484
PFAM: protein of unknown function DUF1116; KEGG: mta:Moth_2121 protein of unknown function DUF1116.
 
     0.769
Noca_1485
PFAM: FdrA family protein; KEGG: ecp:ECP_4036 YahF/FdrA-like protein.
 
     0.754
Noca_1497
PFAM: Hydantoinase B/oxoprolinase; KEGG: rha:RHA1_ro03486 probable hydantoin utilization protein B.
 
     0.747
Noca_1492
PFAM: carbon monoxide dehydrogenase subunit G; KEGG: rha:RHA1_ro03488 possible carbon monoxide dehydrogenase protein G.
 
     0.681
Noca_1491
Xanthine dehydrogenase, molybdenum binding subunit apoprotein; PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: rha:RHA1_ro03489 probable carbon monoxide dehydrogenase large subunit.
 
     0.670
Noca_1496
5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; KEGG: rha:RHA1_ro03487 probable hydantoin utilization protein A.
 
     0.569
Noca_1488
PFAM: Xanthine/uracil/vitamin C permease; KEGG: rha:RHA1_ro03492 possible xanthine/uracil permease.
 
  
 0.568
Noca_4149
Transcriptional regulator, CdaR family; PFAM: purine catabolism PurC domain protein; KEGG: sco:SCO7033 regulatory protein.
  
     0.468
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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