Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Noca_0684PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit; KEGG: mmc:Mmcs_1690 aromatic-ring-hydroxylating dioxygenase, beta subunit. (168 aa)    
Predicted Functional Partners:
Noca_0683
Rieske (2Fe-2S) domain protein; PFAM: ring hydroxylating dioxygenase, alpha subunit; Rieske [2Fe-2S] domain protein; KEGG: mmc:Mmcs_5458 ring hydroxylating dioxygenase, alpha subunit.
 
 
 0.986
Noca_0826
Rieske (2Fe-2S) domain protein; PFAM: ring hydroxylating dioxygenase, alpha subunit; Rieske [2Fe-2S] domain protein; KEGG: rha:RHA1_ro02842 large subunit of ring-hydroxylating dioxygenase.
 
 
 0.919
Noca_2137
PFAM: Rieske [2Fe-2S] domain protein; KEGG: fal:FRAAL6167 hypothetical protein; putative dioxygenase.
 
 
 0.853
Noca_2518
PFAM: Rieske [2Fe-2S] domain protein; KEGG: rha:RHA1_ro04538 ketosteroid-9-alpha-hydroxylase, oxygenase.
  
 
 0.819
Noca_0685
Hypothetical protein.
       0.773
Noca_0686
Phthalate 3,4-dioxygenase, ferredoxin reductase subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sma:SAV1609 ferredoxin reductase.
     
 0.731
Noca_0827
PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit; KEGG: fal:FRAAL3401 putative dioxygenase component, beta subunit.
  
     0.680
Noca_1649
Pyruvate carboxyltransferase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
   
 0.487
Noca_1650
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
     0.483
Noca_2150
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
     0.478
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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