Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
Noca_0785PFAM: large-conductance mechanosensitive channel; KEGG: pac:PPA0491 large conductance mechanosensitive channel. (129 aa)    
Predicted Functional Partners:
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
  
 0.958
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
    0.822
Noca_0786
PFAM: SAF domain; KEGG: rha:RHA1_ro05629 hypothetical protein.
       0.818
Noca_0787
TIGRFAM: putative regulatory protein, FmdB family; KEGG: mmc:Mmcs_4292 putative regulatory protein, FmdB.
       0.650
Noca_0793
TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; KEGG: sco:SCO3179 molybdenum cofactor biosynthesis protein (putative secreted protein).
     
 0.524
Noca_0038
PFAM: Dimethylmenaquinone methyltransferase; KEGG: pol:Bpro_2296 dimethylmenaquinone methyltransferase.
   
  
 0.451
Noca_0788
PFAM: peptidase S45, penicillin amidase; KEGG: sco:SCO3184 putative penicillin acylase.
     
 0.449
nhaA1
Sodium/proton antiporter, NhaA family; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
     
 0.444
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.426
Noca_3128
DNA polymerase III, epsilon subunit; KEGG: fal:FRAAL5108 putative DNA-directed DNA polymerase; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Excinuclease ABC, C subunit domain protein; UvrB/UvrC protein; Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease.
     
 0.424
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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