STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_0798KEGG: sus:Acid_6472 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase. (545 aa)    
Predicted Functional Partners:
Noca_1796
methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: rha:RHA1_ro01456 possible methylmalonyl-CoA epimerase.
 
  
 0.974
Noca_0799
PFAM: cobalamin B12-binding domain protein; KEGG: pfu:PF1946 methylmalonyl-CoAmutase, subunit alpha.
 
 
 0.967
Noca_3591
isobutyryl-CoA mutase small subunit; PFAM: cobalamin B12-binding domain protein; KEGG: sco:SCO4800 isobutiryl CoA mutase, small subunit.
 
 0.952
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.910
sucD
succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.908
Noca_0801
TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; KEGG: sma:SAV2855 lysine arginine ornithine transport system kinase.
  
 0.907
Noca_2128
PFAM: cobalamin B12-binding domain protein; KEGG: hwa:HQ2301A methylmalonyl-CoA mutase, subunit B (cobalamin-binding subunit).
 
 
 0.874
Noca_1798
TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; KEGG: sma:SAV2855 lysine arginine ornithine transport system kinase.
  
 0.833
Noca_0537
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: tfu:Tfu_2674 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit.
    
 0.830
Noca_2130
LAO/AO transport system ATPase; KEGG: pfu:PF1947 hypothetical protein; TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; SMART: AAA ATPase.
  
 0.828
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.