STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Noca_0799PFAM: cobalamin B12-binding domain protein; KEGG: pfu:PF1946 methylmalonyl-CoAmutase, subunit alpha. (148 aa)    
Predicted Functional Partners:
Noca_0798
KEGG: sus:Acid_6472 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase.
 
 0.996
Noca_3544
KEGG: sma:SAV2040 putative methylmalonyl-CoA mutase, coenzyme B12-dependent alpha subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein.
  
 0.950
Noca_3545
PFAM: methylmalonyl-CoA mutase; KEGG: fal:FRAAL4951 methylmalonyl-CoA mutase small subunit (MCM-beta).
  
 0.950
icmF
methylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
  
 
 0.939
Noca_0801
TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; KEGG: sma:SAV2855 lysine arginine ornithine transport system kinase.
 
 
 0.938
Noca_1796
methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: rha:RHA1_ro01456 possible methylmalonyl-CoA epimerase.
 
  
 0.931
Noca_0537
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: tfu:Tfu_2674 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit.
 
  
 0.923
Noca_0536
PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: sma:SAV4876 2-oxoglutarate ferredoxin oxidoreductase, beta subunit.
  
  
 0.916
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.911
sucD
succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.908
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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