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mfd protein (Nocardioides sp. JS614) - STRING interaction network
"mfd" - Transcription-repair coupling factor in Nocardioides sp. JS614
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site (1224 aa)    
Predicted Functional Partners:
Noca_2679
ABC transporter-like protein (795 aa)
   
 
  0.953
uvrA
Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (1019 aa)
   
 
  0.953
Noca_2119
ABC transporter-like protein (836 aa)
   
 
  0.953
Noca_0925
Hypothetical protein (219 aa)
              0.859
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (1166 aa)
     
 
  0.847
Noca_0926
MazG nucleotide pyrophosphohydrolase (233 aa)
   
   
  0.837
Noca_3006
DNA polymerase I (889 aa)
   
   
  0.835
Noca_0317
DNA polymerase III subunits gamma and tau (678 aa)
   
  0.787
Noca_2482
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA (584 aa)
 
 
  0.786
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (360 aa)
   
   
  0.771
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614, Nocardioides, Nocardioides JS614, Nocardioides sp. JS614
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